Pet Remedy's Natural De Stress & Calming formula is a unique and clinically proven formula of Valerian absolute oil with small inclusions of Vetiver, Basil & Clary Sage essential oils. The low concentration of oils is very gentle in its effect and works with your pets own natural calming mechanisms by mimicking GABA (gamma amino butyric acid), which is a natural calming agent present in mammals, birds, and reptiles. The plug in diffuser provides a constant, slow release of Pet Remedy into the surrounding area and lasts up to 60 days.